Our Product :

Autoclaves

Regular Steam Autoclave- RSA RSA are particularly designed for sterilization by steam of heat-resistant and moisture-stable materials such as metals parts, plastics, rubbers, filters, liquid in sealed or vented containers, Clothes, etc. Flexible: It offers the possibility to sterilize packed or unpacked solids and liquids in sealed or vented containers. The high efficient built in steam generator allow to reduce the foot print of the machine. Main Features:

• Large variety of chamber sizes.
• Easy assembling and disassembling (reduced direct labor).
• Possibility of loading any shape/sizes of products.
• Optimization of all process phases.
• Uniform temperature distribution (+0.1⁰C).
• Perfect air removal.
• Low residual humidity.

Component Washing machine

Utensil and Container Washers-UCW UCW is particularly designed for the complete cleaning of the surfaces of utensils, glassware, filling machine parts, IBC containers, etc. Flexible: that it can be used for the process of large variety of products such as minor items, glassware, needles, tubes, drums, clamps, bottles, tanks, collectors, trays and combined materials with the same proven results. Rotating Spray Nozzles concept: Pressurized water and intensive spray action by rotating nozzles. Low (2-3 bar) and high (40-80 bar) water pressure is available. Nozzles completely made of 316L stainless steel with no threads (GMP) type. Spray nozzles of static type for cleaning of external surfaces and of telescopic type for the internal cleaning of large containers (IBC tanks, bins, etc.)
Main Features:

• Reducing of excessive accumulation of products during the process.
• Elimination of mechanical strains.
• No particle generation due to friction and abrasion.
• Enhanced surfaces exposure at process fluids.
• Possibility of loading different patters/sizes of products in one batch (combo-loads).
• Visual and digital (by cameras) check of line- clearance and cleaning.
• Uniform cleaning.
• Uniform heat distribution.
• Full automatic control of water conductivity, TOC and Ph.

Dry Heat Sterilizer-DHS

Dry Heat Sterilizer � DHS DHS is particularly designed for sterilization and depyrogenation by hot air in class 100 (ISO 5) of empty glass containers such as vials, ampoules, bottles and stainless steel parts. Flexible: it can be used for sterilization, depyrogeneation and drying of any solid material resistant to dry heat. While the product drying may be run at temperature adjustable between 50⁰C and 120⁰C. Main Features:

• Reduced foot print.
• Large variety of chamber sizes.
• Easy assembling and disassembling (reduced direct labor).
• Possibility of loading any shape/sizes of products.
• Optimization of all process phases.
• Uniform temperature distribution (+1⁰C).
• Built-in air handling units (air intake and air exhaust with HEPA 14 filters).
• Built-in air recycling wall with HEPA 14 filters.
• Built-in air heating unit.
• Built- air cooling unit.

Tray Dryer-TD

TD are particularly designed for drying solid materials such as powders, fine granulates, machines parts, filters, etc. Flexible: it can be used for drying of any kind of solid material resistant to dry heat. The drying temperature is adjusted between 70�C and 120�C with a temperature deviation of +2⁰C. product cooling up to room temperature. (25⁰C)
Main Features:

• Large variety of chamber sizes.
• Easy assembly and disassembly (reduced direct labor).
• Possibility of loading any shape/sizes of products.
• Optimization of all process phases.
• Uniform temperature distribution (+2⁰C).
• Built-in air handling units (air intake and air exhaust with HEPA 14 filters).
• Built-in air recycling system with recycling wall with HEPA filters (optional).
• Built-in air heating unit.
• Built- air cooling unit.
• Temperature and humidity control.

Terminal Sterilizer -TS

TS are particularly designed for terminal sterilization of liquids contained in sealed containers such as flexible bags, glass bottles, BFS bottles, syringes, cartridges, ampoules, etc. Flexible: it can be used for sterilization any kind container for liquids. From a small pre-filled syringe/cartridge up to large bag/bottle made of glass, PVC, non-PVC, PET, PTFE, Polypropylene, Polythene, etc. Flexibility guaranteed by an automatic differential pressure compensation based on product probes (RTD) temperature measurement (?T).
Main Features:

• Reduced foot print.
• Large variety of chamber sizes.
• Easy assembly and disassembling (reduced direct labor).
• Possibility of loading any shape/sizes of products.
• Optimization of all process phases.
• Uniform temperature distribution (�5�C).
• System to prevent any kind of deformation, damaging and bad coloring of the plastic containers.
• Possibility to have two solutions/typology of process. Air + Steam Mixture and Overheated Water.

Vial Washing Machine

• Vials washing machine is designed with individual water and air cleaning station as cGMP standards.


• The machine ultrasonically cleans (Option).Pressurised spray washes and rinses the interior and exterior of vials with Liquid Media and blows compressed air into and over the exterior of vials.


• Siliconization is also possible and multiple container infeed and exit configuration are available.Automatic Guard opening.


• CIP/SIP of the Piping System.Minimum Dead Leg in the line.

Hot Air Sterilization & Depyrogenation Tunnel

The hot Air Sterilization & Depyrogenation laminar air flow tunnels sterilize and Depyrogenates glass vials. Unidirectional Laminar air flow preheats, Depyrogenates and cools the vials in an ISO 5 environment attaining a 3 log bio-burden reduction of Endotoxins.

• Auto balancing of zones.
• Velocity control and pressure Balancing.
• Sleep and wake functionality, recording devices and multiple infeed and exit configuration are available.
• Automatic Gate opening.
• Sterilization of Cooling Zone.
• Chilling Coil.
• Auto Unloading of Last Vials in Filling Room.

Monoblock Vial Liquid Filling & Stoppering

• The Liquid Filling & Stoppering Machine is Compact Designed Linear Monoblock suitable for widerange of Glass & Plastic Vials.


• Vial Transfer conveyors are designed to handle different Vials without change over.


• Different Filling methods available such as SS Rotary Pumps, Ceramic Pumps & Diaphragm Pumps.


• Also peristaltic Pumps are available.


• Suitable to handle Cytotoxic Products.


• Statistical Check weighing & 100% Check Weighing.


• Experienced designing, manufacturing & Integration of Containments such as VLAF, HLAF oRABS, cRABS & Isolators.

Aluminium Cap Sealing Machine

• The Aluminium Cap Sealing Machine is designed with intermittent motion / continuous motion.


• The intermittent motion RCS alu-crimp caps vials around an indexing star wheel.


• The high speed continuous motion RPC crimps vials around a turret with upto 10 heads.


• Rejection System for Improper & absent Seal.


• Positive Vial Control.


• Vial Height Compensation.


• Adjustable Sealing Pressure.

Ampoule & Vial Washing Machine

• Customized layout in accordance to special enduser's demands.
• Containers feeding from unscrambling units, rotary or bi-flow tables, depending on process and layout configuration.
• Inclined infeed module with ultrasonic bath unit.
• Detergent storage tank with automatic dispensing unit.
• Recycled water tank with temperature control.
• Siliconization station.
• Filtering unit on each liquid flow path.
• Fully sterilizable pumps.
• Vapour extraction unit.
• Automatic draining and drying stations.
• CIP/SIP functionalities.
• Remote assistance.
• Printer and SCDA Interface for production data recording and management.
• Documentation packages for complete system validation.
• Direct connection to sterilization tunnel.

Sterilization & Depyrogenation Tunnel

• Inline connection to upstream and downstream equipment.
• Additional cooling chamber.
• Sterilizable cooling chamber.
• Particle measuring inside the chamber.
• Continuous airflow measuring system.
• Automatic air pressure balance inside the tunnel for consistent positive pressure to avoid air back flow.
• Air speed monitoring and automatic adjustment by means of anemometric system in all chambers.
• Automatic vial discharge at batch end.
• Remote assistance.
• Printer and SCADA interface for the production data recording and management.
• Documentation packages for complete system validation.

Ampoule Filling & Sealing Machine

The AFM series machines are designed to process both closed and open ampoules. Developed to meet current pharmaceutical industry requirements, and to address the needs of the enduser, they are suitable both for liquid parenterals and products that must undergo the lyophilisation process.Their extremely slim design reduces expensive classified area space requirements, though within a conventional clean room, or with other containment systems such as RABS or isolators. It also allows different layout configurations and center of the room or wall installation.
The AFM Series can work as a standalone unit or connected in line with sterilization tunnel (open ampoules). It can be equipped with up to 12 filling nozzles offering a productivity ranging from 30-600 ampoule/minute.

• Customized layout in accordance to special enduser's demands.
• Inline connection to upstream and downstream equipment.
• Wall installation.
• Containers feeding from unscrambling units, rotary or bi-flow tables (depending on process and layout configuration).
• Pre-heating group to process closed ampoules.
• Intermediate tank with level control by means on weighing cell.
• Statistical or 100% IPC.
• Nitrogen purging group before, during and after filling operations.
• Descaled and passivated filling circuit.
• Vials stoppering and sealing/ crimping heads (COMBI version).
• Closures presence control and automatic rejection systems.
• CIP/SIP functionalities.
• Remote assistance.
• Printer and SCADA interface for production data recording and management.
• Integration with conventional LAF units or RABS.
• Preparation for isolation technology.
• Documentation packages for complete system validation.

Auto Tyvek Removal

Filling & Stoppering Machine

The SYFILL series of fiiling and stoppering machines have been specially designed to process already sterile nested containers, such as syringes, cartridges, and vials.Developed to meet current pharmaceutical industry standards and requirements, the SYFILL Series has a particularly compact design that reeduces the space taken in sterile room.

SYFILL machines can be intergarated with conventinal LAF systems, RABS or isolators. They can also be configured for wall installation.The same machine can use 1-10 filling nozzles while keeping the same frame and design in order to cover a wide range of productivity (30-500 containers/minute).